Endometrial Scratching

What is endometrial scratching?
Endometrial scratching is an add-on treatment one can get during their IVF journey. It is widely used by clinics to achieve higher success rates of embryo implantation after the transfer in the uterus. During this procedure, medical experts in the reproductive field will use specific tools, causing a superficial wound to the uterus lining. This will increase the receptiveness of the lining and make embryo implantation easier.


Why choose to perform an endometrial scratching?
In 2005, a study performed in the USA, New Zealand, Australia and Europe identified that approximately 70% of the IVF cycles performed that year were unsuccessful. Embryo implantation is one of the most crucial factors of treatment failure. This is the reason why endometrial scratching was originally inspired.
There are many points during the IVF procedure that an individual can see their plan to achieve parenthood fail. Often, the cause of an unsuccessful IVF round can be identified, with reproductive experts managing a near–total treatment. Although the reasons for failure are almost always explained, many are the cases of a failed IVF cycle attributed to an unknown, unexplainable, and therefore uncurable, reason. This might frighten or disappoint individuals. This is when a doctor will most likely offer to perform an endometrial scratching during the next IVF treatment.
The procedure is performed after it becomes clear that the quality of the embryos is not to be blamed for the unsuccessful pregnancy attempt by the patient.
Procedure
The endometrium is the inside layer of the uterus, where fertilized eggs will seek to implant in order to begin the pregnancy. For a person AFAB to fall pregnant, the embryo must attach itself to the uterine lining (termed implantation). A failed implantation is considered to be the leading cause of an unsuccessful pregnancy, normally attributed to lack of receptivity by the uterus. However, research indicates that lightly scratching the surface of the uterus may highly improve the chances of implantation. This is caused by the following factors:
- Inflammation: Scratching the lining of the uterus is found to cause an inflammatory response, similar to the one caused by scratching the skin. This results in the release of specific hormones and growth factors, which can make the uterine lining more receptive to embryo implantation.
- Genes: Endometrial scratching can activate specific genes that otherwise may not have been activated, to make implantation easier. These genes are important for uterine preparation. Included in the genetic factor expression are laminin alpha 4, glycodelin A, matrix metalloproteinase 1 and others.
The procedure is simple. It takes approximately 15-20 minutes to complete and involves minimally invasive techniques. The doctor inserts a flexible, 3mm catheter into the uterus. The catheter is rotated and moved around. This is what causes the disruption to the lining.
Is it beneficial?
Multiple studies have investigated the effects of endometrial scratching in uterine implantation, with evidence showing contradicting results. Reviews are producing overall beneficial and positive outcomes. However, doctors are noting specific limitations and drawbacks that may cause this technique to not be beneficial for everyone. Risks like uterine perforation, infection and bleeding may be rare, but important. Each unique case needs to be evaluated by a medical professional, in order to assess whether the procedure is appropriate or not.
Parenthood is a beautiful, life-changing journey that every person deserves to embark on. We at Gyn Care IVF are here to assist and accompany you on every step of this journey. With state-of-the-art facilities, renowned medical professionals and a passion for making your wishes come true, Gyn Care IVF ensures an affordable, but qualitative experience. Gain all necessary information about IVF in Athens by contacting us via WhatsApp or E-Mail and enjoy your stay!